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InResident Evil 4, treasure combinations are gemstone patterns inlaid into a valuable item to increase its sales price. The remake has ten variants of these patterns: Duo, Trio, Quartet, Quintet, Two Colors, Three Colors, Two Duos, Four Colors, Duo & Trio, and Five Colors. In the original game, decorating a treasure with different-colored gems was the best combo. However, the new patterns introduced in the remake come with various bonuses that each affect the item’s price uniquely.
Updated on June 05, 2025, by Mohsen Baqery: In the previous updates, we aimed to add more information regarding treasure combos, explaining how you can earn the highest profit using inlay combos. This current update expands on this by addingbulleted lists of each treasure combo’s components and sales price. Additionally, we now have several dedicated sections to describe how gemstone rarities and types may affect your decoration bonuses.
Resident Evil 4’s Treasure Combo Bonuses Explained
The bonus system inRE4works by multiplying the additional value of the gems by a number ranging from ×1.1 to ×2.0. Two blue gemstones, for example, increase a treasure’s value by 8,000. But with the added value of the Dou Combo, their bonus adds up to 10,400.
The following table shows all gemstone combinations and explains their bonuses:
×1.1
Two gemstones with different colors
×1.2
Two gemstones with the same color
×1.3
Three gemstones of different colors
×1.4
Three gemstones of the same color
×1.5
Two pairs of gemstones with the same color
×1.6
Four gemstones of different colors
×1.7
Four gemstones of the same color
×1.8
One pair and one trio of gemstones with different colors
×1.9
Five gemstones of the same color
×2.0
Five gemstones with different colors
The Best Combinations for Treasures in RE4 Remake
Considering the bonus, the best treasure combinations in theRE4remake areFive Colors, Quintet, and Duo Trio.
With the Five Color combo, the goal is to decorate a treasure with five gems of different colors. With Quintet, the goal is to combine five same-colored gemstones. And with Duo & Trio, the aim should be to have a same-colored pair and a same-colored triad of gems on one treasure.
With that being said, here are the most expensive treasure combinations in theRE4remake.
#1. Elegant Crown (Duo & Trio)
The most lucrative combination for the Elegant Crown is a Duo & Trio with two yellow gems and three red beryls. The combo wouldincrease the crown’s price to 108,000 Ptas., making it the most expensive item in the game.
Quintet is also a good combination for the Elegant Crown. With five gems of different colors, its value goes up to 100,000.
#2. Ornate Necklace (Quartet)
To sell the Ornate Necklace for the highest price, the player should give it a Quartet combination. An all-red gemstone decoration increases this treasure’s cost to 59,500, making it one of the most high-priced treasures ever.
#3. Chalice of Atonement (Trio)
Inlaying the Chalice of Atonement with three red beryls boosts its price to 47,600 Ptas. What makes this treasure even more valuable is its viability; the player canpurchase it from the Merchant for 3 Spinels.
#4. Elegant Mask (Trio)
A combination of three same-colored gemstones is the ideal decoration for the Elegant Mask. Attaching all-yellow jewels to this treasure would increase its price to 36,400 Ptas.
#5. Butterfly Lamp (Trio)
Although an average treasure, the Butterfly Lamp with three blue gems is worth 25,200 Ptas. Of course, three yellow stones would up its price even further, but the player is advised to keep those for more precious collectibles like the Elegant Crown.
#6. Golden Lynx (Trio)
Acquiring the Golden Lynx is no easy feat. However, if you manage to obtain one,enhance its value byadorning it with two Red Gems and one Red Beryl. This Trio gem combination is the optimal choice, as the statue features two round and one square-shaped empty slot. Employing the same-color strategy, you can elevate the overall price of this item to 40,000 Pesetas.
Another viable combination for this treasure involvesa Three-Color approach, utilizing a yellow diamond, a sapphire, and an emerald. However, the increase in value closely resembles that of the Trio combination. Therefore, the decision ultimately boils down to the gems available in your inventory.
#7. Flagon (Duo)
The optimal gemstone combination for a Flagon is the Duo. Adorning this item with two same-colored gems yields the highest bonus rate, x1.2. With the Flagon’s base price set at 4,000 Pesetas, the maximum selling price you can achieve is21,600 Pesetas, assuming you utilize two Yellow Diamonds.
Don’t waste your rare gemstones on Flagon. Since the treasure’s base price is low, it is best to enhance it with common gems like rubies.
#8. Splendid Bangle (Dou)
Combiningtwo Red Beryl gems with a Splendid Bangleboosts its value by 21,600 Pesetas, elevating its worth to 25,600 from the base price of 4,000. While this increment may seem modest, it’s worth noting that multiple Splendid Bangles are scattered throughout the game. Thus, this process can be viewed as a recurring and regenerative profit resource.
If you’re planning on saving your rare Beryl,opt for a two-color basic combination instead. With this strategy, you will boost the overall value of the Bangle by a factor of 1.2, resulting in a commendable profit margin. This approach proves particularly advantageous early in your adventure when your treasure-hunting opportunities are restricted.
Best Way to Invest Your Gemstones in Treasures
InRE4 Remake’s campaign, the availability of gemstones is restricted, butcertain types have a higher drop rate. Red Gems, for instance, are more abundant and easier to come by. Therefore, if you aim to enhance the value of common loot, embellishing it with Red Gems is advisable. However, it’s wise toretain rare gemstones like Yellow Diamonds, as they are guaranteed to significantly increase the value of end-game treasures.
How to Find the Best Combination for Treasures
To come up with the best combinations, calculate the final price beforehand or try different patterns in the pause menu. The formula for treasure combinations is simple: Sum the gemstones’ price, multiply it bythe gemstone bonus rate, and add the sum to the item’s base price.
Red gem
3,000
Blue gem
4,000
Yellow gem
7,000
Green beryl
5,000
Purple beryl
6,000
Red beryl
9,000